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Mel seeks medical care, with a nervous Jack by her side. Hope's confusion puts Doc in a tough position. A new doctor joins the practice.
Jack and Brie's father causes friction when he comes into town. An incident at work affects Mel. Doc gets to know his unexpected visitor.
Despite not knowing whether her baby belongs to her deceased husband, Mark or Jack, Mel begins Season 4 with a sense of optimism. For years she yearned to be a mother and her dream is one step closer to reality. While Jack is supportive and excited, the question of paternity continues to gnaw at him. Complicating matters is the arrival of a handsome new doctor, who's in the market to start a family of his own. Hope is still healing from her car accident, and the lingering psychological effects of her brain injury will have profound consequences for both her and Doc. Brie, intent on proving the innocence of the man she loves, unexpectedly finds herself in a closer relationship with Mike and one step closer to Calvin's violent criminal web. Even as Preacher forges a new romantic connection, he can't help but hold out hope for being reunited with Christopher and Paige.