A 74-year-old with breathing difficulties is rushed into Barnsley Hospital, and registrar Dr Nick Mani considers placing the patient in a medically-induced coma to stabilise him. Junior doctor Ashleigh Trimble assesses 70-year-old Dave, whose daughter Sarah fears her dad's confusion and loss of appetite are masking a more serious condition.

Doctors treat an elderly patient rushed into hospital suffering from a racing heartbeat, and a 28-year-old man receives treatment after a motorbike accident. Elsewhere, nurse Richard Jackson meets Graham, a patient with a complex medical history, who has been brought in with the symptoms of a stroke.