Food poisoning hits the cockpit crew on a flight. Lisa Benton takes the biggest challenge of her life when a high-calorie time bomb in the form of a cheesecake is about to explode in the cockpit of a Boeing 747. That explosion of the bomb-hidden-in-a-cake is about to take place at 30,000 feet in — to be exact — the stomachs of Captain March and his co-pilot and flight engineer, all of whom consumed large helpings of the contaminated pastry. 

Lisa Benton succumbs to the charms of a handsome passenger, Sen. Sinclair. Her roommates, Pam, and Marcy aren't faring too well. The males pursuing them are more interested in the mistakenly picked up briefcase in the possession of Pam.