The clock's ticking as the FBI and FBI: Most Wanted teams join forces to hunt down the fugitive terrorists as they get closer to carrying out a plot to destroy a major New York City landmark and cause devastating civilian casualties.

The team jumps into action to find two missing coeds after their roommate Carly Cassidy's older brother is involved in a homicide that took place in their dorm room. Also, Hana becomes distracted when she meets someone online.