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It's the penultimate match of the first round in the Christmas quiz for grown-ups and both teams are doing battle for a place in the semi-finals.
They are the University of Durham, with weather presenter Sarah Keith-Lucas and comedian Ed Gamble, who are playing against Downing College, Cambridge, with the BBC's media editor, Amol Rajan, and their global trade correspondent, Dharshini David.
Jeremy Paxman asks the questions.