This episode of RTS award-winning 24 Hours in A&E explores notions of luck and chance, when a young man is involved in a high-speed car crash and an 18-year-old breaks his leg while playing football. David, who's 29, is airlifted to St George's following a head-on collision at speed. His girlfriend Emily drives for two hours to the hospital, with thoughts of serious internal injuries flashing through her mind. When she gets there she's shocked by what she finds. Darnell has severely broken his leg playing football. Doctors are concerned such a serious break could have long-term implications. Darnell's mum Natalie talks about how she was only 16 when she found out she was pregnant but was over the moon with the news.

Lee, who's 36, is rushed to St George's after being involved in a high-speed road traffic collision. As doctors examine Lee, his wife Emily reveals that Lee lost his best friend months earlier in a similar collision, saying 'It can't happen again, two best friends can't go in the same way.' Lee's CT scans reveal a potentially life-threatening injury to his spleen. Meanwhile, 34-year-old Jeroen has been knocked off his bike on the way to work. The accident was caught on his own GoPro camera mounted on his helmet. As Jeroen is taken for emergency CT scans, his wife Joanna reflects on how they both wanted children together and underwent IVF.