Claire, 46, has been sent to A&E by her GP with chronic back pain, and doctors soon realise she may be suffering a serious underlying spinal injury. Anne Marie has been rushed to St George's following a suspected stroke, and staff have to act quickly to help prevent any long-lasting damage, while five-day-old Gracie is brought in by new parents Danny and Jordan, concerned she has an infected umbilical cord.

Seventy-year-old Jenny is brought in with a suspected stroke, and doctors must confirm the diagnosis and decide whether she is still in time to receive life-changing treatment. Her husband Roy shares the difficult experiences they've faced together and describes Jenny as the rock of the family. Ronnie has come into St George's with severe lower back pain. Doctors assess whether the 29-year-old's pain is due to his kidney stones or something more serious. Ronnie is accompanied by his girlfriend Anneline, who reflects on the similarities between Ronnie and her late father.