Hospital staff at Queen's Medical Centre in Nottingham treat three female university students who have been victims of a spate of needle-spiking attacks. Twenty year-old Kate is rushed in after collapsing in a nightclub and having to receive CPR from a friend when she stopped breathing normally. In the Urgent Treatment Unit 19 year-old Pavni and 21-year-old Sarah meet while waiting for treatment after what they suspect to be needle-spiking. While being treated Pavni talks about the racist abuse she faced growing up and Sarah reveals the impact COVID-19 has had on her university experience.

Sara, 46, is rushed in after a car crash with serious head and chest injuries, and 54 year-old Simon comes in after falling off his bike on his way to buy a helmet. As his condition deteriorates, Simon looks back on his life and the things he wishes he had done differently. Sixteen year-old James comes in with a severed finger after trying to climb a fence.