After their infant daughter received a heart transplant to save her from the same condition that their son died of as a newborn, Cathy and Bill Grinnan made a promise that they would do whatever they could to educate others about heart disease. Despite their personal tragedies, the Grinnan family became crusaders for heart disease research and treatment. Now it's time for someone to give back to them.

In this episode, a Jamaica Queens, New York family finally get their dream house -- two years after a contractor left them without a roof over their heads. With a house rendered unfit for habitation, Lucy Ali and her 12-year-old adopted sons, Paul and Kuran, had been living as urban refugees, hop-scotching from hotel to hotel, to relatives' couches and to a homeless shelter. "Extreme Makeover: Home Edition" brings the Ali house back to life when the design team and over 150 workers rebuild it.