Secrets revealed at a major fundraising gala for the hospital threaten to end a tenuous truce between Dr. Sam Griffith and her father, Griff. Also, cardiothoracic resident Dr. Lex Trulie makes a decision that could alter her career trajectory.

When Amy Taylor is admitted to the hospital accompanied by her sister, Gretchen, with signs of premature heart disease, Dr. Sam Griffith discovers a deeper medical mystery. Also, Griff anxiously awaits the results of his MRI, hoping to get to the root of his troubling symptoms.