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When Karen disappears with Faith, a cryptic call sends Fatima on a tense search, Aaron struggles with doubt and guilt, and all must face how their actions drove her away when she resurfaces.
Gary begs Andi for closure, Chaz and Zac butt heads over Fatima, Maurice nervously welcomes Dylan to his home, and Karen's loved ones search for her and baby Faith.
Everyone's problems must be put on hold when one of their own goes missing, and the circumstances of the disappearance cause them all to fear the worst.
Zac reverts to his old ways when he confronts one of Fatima's clients, Karen finds her salon running differently than how she left it, and Andi unearths even more dirt on Dr. Cruise.
Danni grows impatient with Tony as he enjoys unemployment, Karen confides in Dr. Vaughn about her mental health, and gifts from Fatima's overly generous clients trigger Zac's jealousy.
Sabrina's one-night stand doesn't go as planned, tensions rise between Zac and Fatima over pregnancy plans, and Andi and Dr. Vaughn have surprising news for one another on their first date.
Zac and Karen bond as they reflect on their complicated past, Tamara gives Hayden a brutal wake-up call, and Maurice and Paige take Sabrina out on the town to find a new man.
Maurice teaches a newly single Sabrina about the world of casual hookups, Andi encounters a setback in her legal pursuit of Dr. Cruise, and Zac finds comfort in an unexpected source.
Karen sinks deeper into postpartum struggles, Andi digs into a grave case, Sabrina confronts her betrayers, and Danni, Fatima and Zac face unexpected turns that test their limits.
Despite best efforts, Karen refuses any kind of comforting company while the rest of the Sistas confront their own individual problems as they all rear their ugly heads again.
Zac, Aaron and the ladies lean on one another for support as Karen's life hangs in the balance, and Danni chastises Rich after Sabrina reveals his betrayal.
Karen's suffering is ignored by a dismissive doctor, and desperation sets in as the women search for a doctor who cares.
Zac and Andi try to regroup after Hudson's shocking act, a furious Sabrina confronts Rich, and a city-wide blackout adds further complications as Karen's labor turns dangerous.