As Dr. Erica Cross plans for a wedding, she is shocked to find out her ex-love Doctor Cintron is now working in the ER. Detective Candice and Detective Ryan detain and question Erica's twin brother Eric Cross about a murder that occurred across the street from his home. After coming to the aid of her brother Eric, Erica faces the truth about her relationship with Doctor Bradley.

After having made a pact to get rid of the local sex trafficking ring, Eric tortures Chauncy; a street thug, for answers about the missing girl Keisha Jarvis. Doctor Cintron admits his true feelings to Erica which she does not reciprocate. Detective Ryan sends Detective Candice home after she shows up to a murder scene intoxicated. While in the ER, Erica suspects a patient of sex-trafficking.