Reginald hides the embarrassing growths on the back of his head with knitted hats. Jackie has lived with her huge shoulder lump for nine years. Leonardo has a chilling-looking growth on his head, but the thought of surgery terrifies him.

Larry has a hanging thigh growth so large that the weight of it makes his leg go numb. Cheerleader Bailee has a disappearing back bump she has named Ralph. With three complicated skin conditions, Ashley's case is considered a "skin nightmare."