Musician Kayla has itchy eczema everywhere, making it difficult to play her guitar. Juan was bullied so badly over the painful bumps he has on his neck and torso that he dropped out of high school. Teresa has a mysterious, deflating arm growth.

Luke has hundreds of lumps on his body that he has been hiding from his in-laws for over nine years. A trio of skin conditions cause Tanisha tremendous stress. John has been avoiding family gatherings since being teased about the huge lump on his neck.