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The war between the 100 and the Kobra Cartel rages on, with tragic consequences. Meanwhile, Lynn continues her experiments. And both Lynn and Jefferson have individual counseling sessions.
Jefferson Pierce is still mourning the death of his long-time friend Detective Henderson. Meanwhile, Gambi is presented with an interesting opportunity. Lastly, Lynn and Jefferson are still not able to see eye to eye.
Jefferson is feeling even more lost after a frustrating therapy session. Meanwhile, Anissa continues to care for a still comatose Grace. Lastly, Lynn has a breakthrough.