Mariana attempts to understand the vanity, insecurity and greed that's driving the unregulated, billion-dollar black market in body-enhancing drugs.

Mariana retraces one of the world's most intractable smuggling routes, following cocaine's path from a remote Peruvian valley through Colombia's Caribbean coast, all the way to the streets of Miami. Despite the decades-long U.S. War on Drugs, cocaine production is at an all-time high, and Mariana meets some of the makers, smugglers, drivers and teenage backpackers who risk their lives to deliver America's favorite party drug.