The arrival in the hospital of Carolina, struck by a mysterious pathology, causes a series of conflicts between Andrea and Agnese that they must overcome together for the sake of their daughter. The attention of the young residents, on the other hand, is catched by an eye-catching influencer, and Alba cannot hide her jealousy for Riccardo.

Andrea is certain that he has finally broken through Agnese's heart and, in the wake of romanticism, proposes to organize a wedding in the hospital for a patient in critical condition. Meanwhile, an unexpected proposal from Gabriel upsets the balance within the group of residents.