The discovery of the medical record of the patient dead by mistake makes Andrea trying and reconstruct what happened before the shot that erased his memories. Marco, responsible for that death, and Agnese are not very cooperative. Alba and Riccardo struggle to re-establish their relationship and even between Gabriel and Elisa things get complicated.

The arrival in the hospital of Elisa's older sister, a nice and charming actress, makes the young resident inexplicably even more sour and grumpy. Andrea continues to dig through the years that the amnesia has erased, while Agnese is unable to hide her jealousy for the growing closeness between Giulia and the doctor.