Andrea is certain that he has finally broken through Agnese's heart and, in the wake of romanticism, proposes to organize a wedding in the hospital for a patient in critical condition. Meanwhile, an unexpected proposal from Gabriel upsets the balance within the group of residents.

The discovery of the medical record of the patient dead by mistake makes Andrea trying and reconstruct what happened before the shot that erased his memories. Marco, responsible for that death, and Agnese are not very cooperative. Alba and Riccardo struggle to re-establish their relationship and even between Gabriel and Elisa things get complicated.