Agnese is surprised to find Manuel's mother hospitalized, the child she has in foster care with Davide, and with whom things don't seem to go too well. Agnese will have to question everything she thinks she knows, just when Andrea seems to want to be closer than ever. While Damiano's choices seem to open an insanable rift between him and Giulia, Gabriel finally decides to open up with the psychologist.

While the doctors are busy solving the delicate case of a deafblind boy, Cecilia makes Doc an unexpected offer, triggering the jealousy of Agnese and Giulia. Meanwhile, Riccardo discovers something about Doc that puts him in a deep crisis. Gabriel makes a shocking proposal to Elisa, putting her in front of a difficult choice.