While the doctors are busy solving the delicate case of a deafblind boy, Cecilia makes Doc an unexpected offer, triggering the jealousy of Agnese and Giulia. Meanwhile, Riccardo discovers something about Doc that puts him in a deep crisis. Gabriel makes a shocking proposal to Elisa, putting her in front of a difficult choice.

Close to become Chief once again, Doc is forced to make a painful confession in front of the whole department. As doctors try to save the life of a young soldier with inexplicable symptoms, Agnese begins to investigate.