A strong mouse says that he will become the heavyweight champion of the world. But his grandma (who is just as strong) doesn't want him to fight. So that night he sneaks off to the fight, which Granny hears on the radio. Granny is so concerned she goes to the arena to stop him from fighting...but fate plays a hand.

This cartoon combines two nursery rhymes to illustrate the ill-advised marriage of Old King Cole to the Woman in the Shoe and the King's unfortunate attempts to keep her "many children" under control. In the end, these all precipitate a nervous breakdown in Old King Cole.