After losing everything, Desiree Wood takes a second lease on life as a long-haul trucker. Alongside an irreverent group of women drivers, she fights for a life on the road. In a rapidly changing labor landscape, Desiree and her sisterhood of truckers rally against the crushing forces of an industry that is indifferent to their survival.

In a remote Siberian coal town, homemaker-turned-journalist Natalia Zubkova investigates an abandoned mine fire releasing toxic gas into residential homes. When her reporting goes viral, government officials launch an aggressive cover-up campaign, putting her directly in their crosshairs.