Trisha Goddard and Dr Amir Khan help two people in desperate need of a life-changing, or even life-saving, intervention. They take control of their lives for eight weeks to show them how they can take control of their own lives forever. The first duo are sports coach Adam, who turned to comfort eating after a bad break-up, and fast-food addict Jackie, who is on a fast track to diabetes.

Trisha Goddard and Dr Amir Khan help a busy mum and an entrepreneur, both in desperate need of a life-changing intervention. For busy mum Zoe, the only thing sweeter than her children is her sweet tooth, but her lifestyle rapidly needs to change, while entrepreneur Dennica needs to take action with the menopause looming.