When Dean comes down with the chicken pox on his way to a hunting trip with Bill and Grandaddy Clisby, Lillian forces the three of them to quarantine together. Clisby pushes homemade remedies on them out of his mistrust of doctors, but he's forced to reckon with this when Dean's condition worsens.

Bill is excited to have made tenure at the university, only to find that his focus on career and family has cost him his spot in his band. Lillian encourages Bill to write and perform solo, especially as an attractive young jazz singer approaches Bill to collaborate. Meanwhile, Bruce adjusts to living at home.