Walter and Maude are planning on taking a second honeymoon to Italy, however, the day their plane leaves, Maude gets a tetnus shot which results in a rash. She immediately hotfoots it down to the doctors office where she encounters a busy preoccupied doctor who prescribes her medication but doesn't advise her on how to take it, resulting in an overdose, cancellation of the honeymoon and a possible malpractice suit.