The pets of Central Michigan are in a jam, and it's up to PVS to get them unstuck. Dr. Pol plucks porcupine quills from a Mastiff's nose, Dr. Nicole pulls three feet of string from a cat, and Dr. Lisa unhooks a dog from a fishhook. An emergency case sends Dr. Pol out on a farm call to treat a horse with choke, while Dr. Brenda has her hands full with pregnancy checks on a herd of rowdy cows.

The Pol's welcome a new foal to the family as the warmer spring temperatures turn up the heat on animal emergencies. Dr. Brenda's knee snaps while saving the life of a mare. Dr. Pol is called out to treat five calves that are struggling to grow. Dr. Nicole plucks quills from a curious Chihuahua, and Dr. Lisa treats a cat with a blocked bladder.