Hardie arrives in Medicine River to help set up a new office. He is greeted at the office by an employee who is the son of a Cheyenne chief he knew when the boy was young but the locals are unhappy he is to be the driver on the route.

Jim Hardie is sent by Wells Fargo to Comanche, Texas to find the Rucker brothers who are hanging around there. Unknown to Hardie, John Wesley Hardin is there, a cousin to the Rucker brothers and still holding a grudge against Hardie.