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Lupin runs out of money because of his long detention, so he decides to steal the Mona Lisa and sell it to a millionaire.
Detective Zenigata tries to stop Lupin's escape attempts from the Italian prison he has been confined to. His first problem being to convince the warden that Lupin is a escape problem.
When Lupin steals a diamond that has the power to change a individual's personality, Lupin ends up losing the diamond.