The mysterious criminal mastermind known as "The Voice" returns and traps Reese and Fusco in their own precinct with several armed gang members and the latest POI. Also, Root makes a shocking discovery.

The team must unravel a conspiracy and stay ahead of the Secret Service when the President of the United States becomes their newest POI. Also, Finch separates himself from the team and considers taking drastic action to combat Samaritan.