The Master's familiar approaches Vanessa and tells her that she has met the Master once before at the Banning Clinic. Meanwhile, Malcolm and Kaetenay arrive in the U.S. to hunt Ethan, who is traveling with Hecate. In London, Caliban finds the wife and child of his former life, while Lily and Dorian recruit their first soldier.

Hecate and Ethan travel across the desert, struggling to survive, while the marshals follow them and Malcolm and Kaetenay follow the marshals. In London, Victor and Henry continue their experiments to perfect Henry's serum.