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It's the end of the world as Chuck's death extinguishes the sun. Desperate, the Winchesters, Castiel, Crowley, and Rowena come up with a plan... but to succeed, one of them will have to die.
To defeat Amara, Sam and Dean will first have to help Chuck and Lucifer reconcile. Once they do, they then must gather the forces of Heaven, Hell, and Magic to weaken Amara so that Chuck can defeat her. However, everything doesn't go quite according to plan.
The 11th season of this supernatural series begins with the Winchesters dealing with repercussions of releasing The Darkness on Earth. Sam and Dean Winchester are approached by a young deputy sheriff, Jenna, who reveals that people have been going rabid and starting killing sprees. Can the violent infection be cured?