A college student wearing a rabbit mask kills a man in Minnesota, and Sheriff Donna calls in Sam and Dean for help. They soon deal with the rabbit, but a harlequin and then a clown attack the local high school coach. Meanwhile, Dean finds Sam praying to God.

While Sam enters Hell with Crowley and Rowena to confront Lucifer and seek his help defeating Amara, Dean investigates the scene of Amara's recent killing and discovers that she has plans for him.