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Sam and Dean try to escape the bunker after Ketch turns it into a deathtrap. Meanwhile, the brainwashed Mary goes after Jody and Alex, and Hess puts Phase Two of the Brit's plan into action.
When Eileen turns up dead, torn apart by a hellhound, Sam and Dean realize that someone is killing the American Hunters. Meanwhile, Mary asks Ketch for a favor.
As Kelly prepares to give birth to Lucifer's son Jack, the Winchesters team up with two unexpected allies to stop Lucifer.