Sam and Dean get a lead on the last item they need to open the rift: the Seal of Solomon, at a Men of Letters chapterhouse in Rhode Island. They soon discover something else: a woman imprisoned there for over 80 years. Meanwhile, Asmodeus teaches Ketch his place in the demon prince's hierarchy.

While Castiel goes to Heaven to try and recruit help, Sam and Dean learn that Rowena is killing people in Portland... and Death has an interest in stopping her.