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While Sam, Mary, and Bobby follow a lead in Duluth, Nick and Jack pay visits to people from their pasts.
As they search for the missing Dean, Sam and his new band of Hunters--Mary, the Apocalypse World Bobby and Maggie, and Jack--take on a demon who wants to use a hostage Castiel as a bargaining chip to have Sam help him become King of Hell. Meanwhile, Michael travels the world looking for someone who he can work with
Dean discovers that he has a scar on his arm similar to the blade that was used to kill Kaia, and he and Sam set off to Sioux Falls to team up with Jody and find out who has a weapon capable of hurting Michael. Meanwhile, Castiel tries to restore a hexed young girl with Jack's help.
When Sam and Dean join forces with an unexpected ally, the outcome will alter the course of two lives. Meanwhile, Heaven faces an attack from a dark force, driving Castiel to make an enormous sacrifice to make things right.