Dean discovers that he has a scar on his arm similar to the blade that was used to kill Kaia, and he and Sam set off to Sioux Falls to team up with Jody and find out who has a weapon capable of hurting Michael. Meanwhile, Castiel tries to restore a hexed young girl with Jack's help.

After Maggie disappears while checking out a ghoul sighting, Sam and Dean go to rescue her. They meet up with Mary and Bobby, and run into a number of bizarre manifestations.