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Sam and Dean respond to a frantic call and together along with Castiel, Jack and Jody, assist in an extraordinary and heartbreaking rescue. Billie surprises everyone with a visit to the bunker.
Sam and Dean press their luck in a winner-takes-all game of pool. Meanwhile, Castiel hunts down a would-be murderer, but not for reasons one might think.
A search for the one thing that may give the Winchesters an edge against God leads Sam and Dean to Jo's door and to a secret that may have died with Ruby. Meanwhile, Castiel asks Jack to do the unthinkable to help the brothers in their quest.
The epic journey of the Winchester brothers come to a close as Supernatural enters its final season. Sam and Dean have battled demons and angels, mythical creatures and monsters, in a seemingly unending quest to save the world. But in the final battle of the show's 15th season, they face off against God Himself, refusing to kill their surrogate nephilim son Jack, and thus bringing about God's decision to end this reality once and for all...