Set after the events of the Battle of New York, S.H.I.E.L.D. Agent Phil Coulson assembles his own team of skilled agents and operatives including Melinda May, Grant Ward, Leo Fitz, Jemma Simmons, and newly-recruited Skye investigate several dangerous cases including the Project Centipede and its leader, The Clairvoyant, while Coulson also searches for answers surrounding his mysterious resurrection.