Hunted and running out of solutions, Coulson puts his team right in the line of fire in the hopes of saving them all. But with General Talbot, Hydra and Creel all on the attack, can they possibly survive? Meanwhile, a mysterious Doctor harbors some dangerous secrets that could destroy one of our core team members.

While on a mission to learn more about the secrets of the mysterious writing, Coulson finds himself attacked by the only person he can trust: Agent Melinda May. Meanwhile, the rest of the team is trapped in an explosive situation, and it's up to Fitz to save them -- but is he up to it?