Warren's Apocalyptic Dream of a Black Rainbow sends our heroes on a mysterious new mission to save the Apocalypse from something even worse. Warren awakens from a coma to find herself in ZONA two years later, with Murphy seemingly cured, and the rest of our heroes either dead or fighting for their lives against unkillable "MAD-Z's" caused by an evolving Zombie Virus.

By the time Warren and the others make it to the refugee camp, Red and Sun Mei have mysteriously vanished along with everyone else. After convincing 10K to give up the search for Red, Murphy and the others decide to head to Numerica with Sarge -- but Warren has her own plan. Driven by her dream, Warren is compelled to head east instead of north.