Jamie and Claire head into the wilderness, in search of a place to call home, but their adventure takes a dark turn when a fierce storm separates them. In the 20th century, Roger and Brianna's relationship heats up during a romantic road trip, but once they get down to brass tacks, both realize that they aren't on the same page.

Claire's medical expertise proves invaluable, but she begins to fear for her life when tragedy strikes her patients' household; Jamie and Young Ian travel to a nearby town to recruit settlers for Fraser's Ridge.