As Tammy and Carter continue to investigate the suspicious death aboard a COVID-infected humanitarian ship offshore, Pride and the team discover that the PPE they were sent to distribute may hold the key to finding the killer. Also, Rita returns to New Orleans to surprise Pride, Wade helps a grieving woman who can't find her brother who died from COVID-19, and Patton and his goddaughter get into a heated argument.

As the NCIS team continue to investigate the murder of an officer who was about to whistle blow on police misconduct within NOPD, Pride must get creative in order to finally get rid of the dirty cops. Also, the Mayor asks Pride to join her new task force to address systemic issues plaguing their city and, as Covid continues to overwhelm the system, Wade finally addresses the toll it's taken on her.