When President Dalton gets word that the world's most wanted terrorist, Jibral Disah, is hiding in Islamabad, he sends the "Murphy Station" – Henry, Jane and Jose – on a dangerous mission to eliminate the threat. Also, Elizabeth and Henry go to couples therapy.

When Elizabeth (Téa Leoni) receives shocking news about an important political operative, she navigates a tricky political situation with President Dalton, who she learns may be considering replacing her as Secretary of State. Also, Stevie (Wallis Currie-Wood) and Jareth (Christopher O'Shea) get engaged.