Elizabeth visits the Middle East to finalize a deal to bring U.S. troops home, but complications arise when a local woman's life is threatened by rumors of a romance with one of Elizabeth's staffers. Also, Henry provides relationship advice to Elizabeth's brother, Will.

While Elizabeth is away on a retreat thinking about her presidential campaign, her staff tries to secure an international agreement to protect citizens who have been displaced due to global warming. Also, the staff works to contain a measles outbreak that threatens the life of Daisy's daughter, Joanna.