Damon goes with Elena and Bonnie to visit Whitmore College, where Professor Shane is taking over the Occult Studies classes formerly taught by Bonnie's grandmother. At a fraternity costume party, Damon takes advantage of the wild scene to give Elena a lesson in choosing a victim. Rebekah's attempt to buy Matt's forgiveness falls flat, but she is intrigued by unexpected news from Klaus. When Stefan questions Klaus about Connor's motives, Klaus reveals a long-ago encounter with a powerful group of vampire hunters, but it's Rebekah who delivers the information that stuns Stefan.

Terrifying hallucinations leave Elena shaken and confused, causing her to make a dangerous mistake. After giving Stefan some very disturbing news about Elena, Klaus takes matters into his own hands. Professor Shane reveals a story of ancient witchcraft to Damon and Bonnie. With help from Klaus and Stefan, Jeremy begins a new chapter in his life. Finally, Elena makes a painful personal confession to Stefan, and Matt gives Damon startling new information about Professor Shane.