Car bomb explodes in front of a busy café, killing the driver and a number of the cafés patrons, and injuring others. Since the car was registered to a prominent Middle Eastern man with U.S. government ties, Agent Booth calls Dr. Brennan into the case to help with the identification of the driver. Once the driver's identity is revealed, Brennan and Booth uncover clues that lead them in an unexpected direction - on the trail of a terrorist before another murder is committed. Meanwhile, Brennan and her team discover that Booth is seeing a woman, which inspires Angela to look further into Booth's personal life in hopes of convincing Brennan that she has a chance for romance with Booth.

When a human arm is found inside the stomach of a black bear, Brennan and Booth travel to Washington state to investigate. They search a small town for clues and discover that ritualistic cannibalism is involved.