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Brennan is in New Orleans helping identify bodies after hurricane Katrina when she wakes up in her hotel bathroom covered in blood and with no memory of the last two days.
The team gets a case of pirate fever when a dead body is found clutching a 300-year-old finger bone. Not only does the team need to solve the murder, but they may also prove the existence of a long sought after pirate treasure.
Booth and Brennan investigate a case of illegal organ harvesting after Brennan discovers why the daughter of FBI Deputy Director Sam Cullen is dying of a rare form of lung cancer.