The team investigates the murder of a police officer that sends shockwaves through both the Jeffersonian and FBI teams. Behavioral analyst Karen Delfs is assigned to work with Booth on the investigation and lends her professional assessments on who the cop killer could be, while Cam must make some decisions in her personal life and the entire team re-evaluates what is truly important to them.

The team investigates a body found in a car crash, the remains of which belong to a founder of a men's rights organization who may have been the victim of domestic abuse. As Brennan learns more about the tenets of the victim's organization, which claims middle-aged white men are oppressed and feminists are man-haters, Brennan uncharacteristically loses her cool during an interrogation and assaults the organization's co-founder. Meanwhile, Angela and the team struggle to deal with Hodgins post-wheelchair bitterness and Booth is convinced Brennan is a jinx for the Philadelphia Flyers.