The gang tries to help Sheldon when he becomes stuck in a rut at work by increasing his anxiety level. Howard teases Raj with a new game called "Cinnamon or Emily?"

Wolowitz receives some shocking news as everyone prepares for the reopening of Stuart's comic book store. Penny teaches Sheldon how to "let it go," but can't follow her own advice after she learns something infuriating about Amy. Also, Leonard and Raj think they spot Nathan Fillion at a restaurant.